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erj ersjournals com content 59 1 2102730Overview Tezspire is a medicine used to treat adults and adolescents (12 years of age and older) with severe asthma It is used as an additional treatment in adults and adolescents with severe asthma that is not adequately controlled by a combination of high-dose corticosteroids taken by inhalation plus another asthma medicine There are a vast number of asthma medications on the market, and thus, the pharmacist should keep a track of what the patient is taking and ensure that no adverse reactions are developing Today, many communities have an asthma clinic staffed by a nurse, where the disorder is monitored, and the patient is educated Asthma is a heterogeneous disease affecting approximately 14 million people living with the disease in the European Union and an estimated 339 million people worldwide 7,8 Up to 10% of asthma patients have severe asthma 9,10 Despite the use of inhaled asthma controller medicine, currently available biologic therapies and oral corticosteroids erj ersjournals com content 55 1 1900588--- astrazeneca com tezspire-approved-in-the-eu-for-the-treatment-of-seve err ersjournals com content 24 137 474The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances ( e g medication availability) This article summarizes key recommendations from GINA 2021, and the evidence underpinning recent changes GINA recommends that asthma in adults and Asthma is one of the most common chronic non-communicable diseases worldwide and is characterised by variable airflow obstruction, causing dyspnoea and wheezing Highly effective therapies are available; asthma morbidity and mortality have vastly improved in the past 15 years, and most patients can attain good asthma control However, undertreatment is still common, and improving patient and Identified national asthma programmes in Europe are listed in table 1 More details about the programmes and their results are summarised in the tables E1 and E2 The first European National Asthma Programme was the Finnish 10-year programme (1994–2004), which has been the model for other European and non-European programmes --- ema europa eu en medicines human EPAR enerzair-breezhalerPARIS and TARRYTOWN, NY - May 7, 2019 - The European Commission has approved Dupixent ® (dupilumab) for use in adults and adolescents 12 years and older as an add-on maintenance treatment for severe asthma with type 2 inflammation characterized by raised blood eosinophils and or raised fractional exhaled nitric oxide (FeNO), who are inadequately controlled with high dose inhaled europepmc org article nbk nbk531455--- sanofi com en media-room press-releases 2019 2019-05-07-13-00-00-1818457This document provides clinical recommendations for the management of severe asthma Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the European Respiratory Society American Thoracic Society Task Force's questions The evidence was appraised using the GRADE (Grading of Recommendations, Assessment, Development and Enerzair Breezhaler is an asthma medicine for inhalation It is used for maintenance (regular) treatment in adults whose asthma is not controlled well enough with inhaled long-acting beta-2 agonist together with a high dose of an inhaled corticosteroid It should be used for patients who have had at least one asthma attack (exacerbation) in the --- ema europa eu en medicines human EPAR tezspire--- thelancet com journals lancet article PIIS0140-6736(22)02125-0 fulltext
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