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--- ncbi nlm nih gov pmc articles PMC4190613Sprycel is indicated for the treatment of children and adolescents aged 1 year to 18 years with Ph+ chronic phase CML 2 1 2 Epidemiology and risk factors, screening tools prevention CML is relatively rare in both adults and children, with rates increasing with increased age; rates peak in the age range of 65-74 years --- ema europa eu en medicines human EPAR sprycel--- sprycel com financial-support costen wikipedia org wiki DasatinibLeukaemias On 27 January 2022, the European Medicines Agency’s (EMA’s) Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Dasatinib Accord, intended for the treatment of Philadelphia chromosome positive (Ph+) acute lymphoblastic Sprycel is a cancer medicine It is used to treat adults with the following types of leukaemia (cancer of the white blood cells): chronic myeloid leukaemia (CML) in the ‘chronic’ phase in newly diagnosed patients who are ‘Philadelphia chromosome positive’ (Ph+) In CML, granulocytes (a type of white blood cell) start growing out of control --- ema europa eu sprycel-h-c-000709-x-0056-g-epar-assessment-report-vari Following imatinib treatment, early molecular response rates at 3 and 6 months (BCR-ABL1 ≤ 10% IS) range between 60 and 80% At one and 5 years, MMR rates range between 20–59% and 60–80% For adult patients receiving SPRYCEL, the list price is $18,246* per month Most patients will pay less Call Bristol Myers Squibb Access Support at 1-800-861-0048 to request an Insurance Benefits Review † and co-pay card information If you have commercial insurance:The cost for bringing a new cancer drug to market is reported to be ∼$1 billion 3 This much-argued-about figure, which some independent experts put as low as $60 to 90 million, 4 includes the cost of development of the new (successful) drug and all other drugs that failed during development, and ancillary expenses including the cost of conducting the clinical trials required for approval In Europe, price reductions for biosimilars are expected to range from 20 to 40%, with a few cases being higher According to estimates, cost savings will amount to more than EUR 10 billion between 2016 and 2020 in the EU5 countries [ 11 ] --- ema europa eu en documents sprycel-epar-medicine-overview_en pdf27 In Europe, considering a generic imatinib price of $4,000 year, a sustained deep molecular response rate of 0 66 for second generation TKI, a willingness-to-pay of $50,000 QALY, and maximized QALY improvement, the price of second generation TKI should not exceed $9,321 year --- nature com articles s41375-020-0776-2Dasatinib, sold under the brand name Sprycel among others, is a targeted therapy medication used to treat certain cases of chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) Specifically it is used to treat cases that are Philadelphia chromosome -positive (Ph+) [3]--- ncbi nlm nih gov pmc articles PMC6658341Sprycel is a cancer medicine It is used to treat adults with the following types of leukaemia (cancer of the white blood cells): • chronic myeloid leukaemia (CML) in the ‘chronic’ phase in newly diagnosed patients who are ‘Philadelphia chromosome positive’ (Ph+) In CML, granulocytes (a type of white blood cell) start growing out of --- esmo org ema-recommends-granting-a-marketing-authorisation-for-generi --- ncbi nlm nih gov pmc articles PMC6465746
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