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--- psychiatrictimes com bupropion-after-nonresponse-or-partial-response- Wellbutrin is an antidepressant medication commonly prescribed for the treatment of depression Unlike many antidepressants that are SSRIs or SNRIs, Wellbutrin is an NDRI (norepinephrine and dopamine reuptake inhibitor) Norepinephrine and dopamine are two neurochemicals—chemicals that impact the nervous system—that can affect mood Issue 3 While SSRIs and SNRIs are valuable in the treatment of major depression, partial response or nonresponse occurs in many patients Research has found that bupropion was the most frequently chosen agent for addition to an SSRI after inadequate response This is the third in a series of occasional columns that aim to help clinicians Objective: To compare the benefits and risks of bupropion and selective serotonin-reuptake inhibitors (SSRIs) in adults with depression Data sources: MEDLINE (1966-September 1999), Embase (1980-August 1999), PsyclNFO (1887-August 1999), International Pharmaceutical Abstracts (1970-August 1999), and CIANHL databases were searched --- medicalnewstoday com articles drugs-wellbutrinen wikipedia org wiki BupropionWellbutrin was used to relieve the symptoms of depression in Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD) Generic bupropion is available and bupropion is also marketed under other brand names such as Aplenzin (also for depression) and Zyban (for smoking cessation) 3 Downsides pubmed ncbi nlm nih gov 11793630The 32% acute-phase attrition rate is in line with the average 33% rate found in four other 8-week bupropion vs SSRI randomized trials in MDD (N=1011) (Thase et al, 2005) The lack of differential drug effects that we observed during the continuation phase may be explained by the high cumulative 6-month attrition, and low variance in ideation because of robust acute improvement --- webmd com depression drugs-treat-depression--- brightside com blog is-wellbutrin-an-ssri-snri-or-ndriIs Wellbutrin an SSRI? No, Wellbutrin is not a selective serotonin reuptake inhibitor (SSRI) Instead, it belongs to a class of drugs called norepinephrine and dopamine reuptake inhibitors (NDRIs) These medications include Mirtazapine (Remeron) Bupropion (Wellbutrin) Tricyclic antidepressants (TCAs) have been used since the 1950s to treat depression Is Wellbutrin an SSRI? No, Wellbutrin isn’t a selective serotonin reuptake inhibitor (SSRI) It belongs to a class of drugs called norepinephrine and dopamine reuptake inhibitors (NDRIs) Bupropion may also be helpful when prescribed “off-label” for depression due to bipolar disorder, attention deficit hyperactivity disorder (ADHD), and sexual dysfunction due to SSRI antidepressants “Off-label” means that it hasn’t been approved by the Food and Drug Administration for this condition --- nami org About-Mental-Illness Treatments Bupropion-(Wellbutrin)--- drugs com tips wellbutrin-patient-tips--- ncbi nlm nih gov pmc articles PMC3260969Bupropion 1: 1 mixture (racemate) Clinical data Pronunciation b j uː ˈ p r oʊ p i ɒ n bew- PROH -pee-on am-fa- BEW -teh-moan Trade names Wellbutrin, Zyban, others Other names Amfebutamone; 3-Chloro- N - tert -butyl-β-keto-α-methylphenethylamine; 3-Chloro-N-tert-butyl-β-ketoamphetamine; Bupropion hydrochloride AHFS Drugs com Monograph MedlinePlus a695033 License data EU EMA: by INN psychcentral com drugs wellbutrin
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